Genetics?

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Carla
Posts: 16
Joined: Sun Feb 14, 2010 6:39 pm

Genetics?

#1 Post by Carla »

Hi all.

I have a question about genetics.. In my case, my parents are from the same zone (a rural zone), and so, I suppose they may have common ancestors.. This may sound weird to some people, but I think there may be a connection.

Have any of you, with maxilla/mandibular problems, wondered about this? Are your parents from the same zone(rural zone/village), and so, is it possible they have common ancestors?

35ksmile
Posts: 52
Joined: Fri Nov 19, 2010 8:06 am

Re: Genetics?

#2 Post by 35ksmile »

everyone's parents have common ancestors, depends how far you wanna look back

i doubt it's really statistically significant.

i guess it could be interesting to see the effects of inbreeding on human morphological phenotypes but the truth is there are just wayyyy too many confounding variables and it would be tough to get a big enough sample size.

the best indicator imo would just be a familial history of jaw issues. if there is a history and your family is from a small, reproductively isolated area then sure your chances will probably be greater, but once you hit about 3 or 4 degrees of separation it's not really all that significant in the slightest (we're talking like less than 1% relatedness at that point)

freakyteeth
Posts: 118
Joined: Tue Aug 28, 2007 9:58 am
Location: Michigan
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Re: Genetics?

#3 Post by freakyteeth »

interesting. If you read about my mutation (the AXIN2), the only other family described in the literature is from Finland. My mom's side is from Poland.
Braces 1986 & Sept 2007 (age 34)
severe class II impinging overbite
17 missing teeth (genetically)- AXIN 2 genetic mutation
Jan 2010 - genioplasty w/mandibular bone graft (from chin bone)
Jul 2010 - 4 mandibular implants. FAILED
Oct 2010 - re-placement of 3 implants, hardware removal
03/29/2011 - BSSO and 3 piece Lefort I
Sept 2012 - Upper jaw - 4 implants w/bone graft.
Jan 2016 - upper hardware removal, extensive upper bone graft

crookedsmile1
Posts: 9
Joined: Sat Aug 28, 2010 2:49 pm
Location: Northern California

Re: Genetics?

#4 Post by crookedsmile1 »

In some royal families in the past, underbites were actually considered the norm due to the high amount of inbreeding. And as time progressed, the underbites got more and more deformed through royal intermarriage. Genetics is a very complicated subject but through this case of the royal family a lot of research on heredity can be made since all of their ancestors are so well documented.

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